PHTHALAZINE DERIVATIVES AS PYRUVATE KINASE MODULATORS

The invention relates to compounds of formula (Ia) and to their use in treating or preventing an inflammatory disease, a disease associated with an undesirable immune response, cancer, obesity, a diabetic disease or a blood disorder: wherein RA, RB, RC and RD, X, Y1, Y2, Y3, Z1, Z2 and m are as defi...

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Bibliographische Detailangaben
Hauptverfasser:	COUSIN, DAVID, BARBA, OSCAR
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The invention relates to compounds of formula (Ia) and to their use in treating or preventing an inflammatory disease, a disease associated with an undesirable immune response, cancer, obesity, a diabetic disease or a blood disorder: wherein RA, RB, RC and RD, X, Y1, Y2, Y3, Z1, Z2 and m are as defined herein. L'invention concerne des composés de formule (Ia) et leur utilisation pour traiter ou prévenir une maladie inflammatoire, une maladie associée à une réponse immunitaire indésirable, un cancer, l'obésité, une maladie diabétique ou un trouble du sang : formule dans laquelle RA, RB, RC et RD, X, Y1, Y2, Y3, Z1, Z2 sont tels que définis dans la description.