CONDITION-ACTIVATABLE NUCLEIC ACID CONSTRUCTS AND THEIR USES FOR TREATING NEUROLOGICAL DISEASES

Provided herein include methods, compositions, and kits suitable for use in preventing and treating a neurological disease or disorder. The method can comprise administering to a subject in need thereof a composition comprising conditionally activatable small interfering RNA (siRNA) complexes. L...

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Bibliographische Detailangaben
Hauptverfasser:	HAN, SI-PING, KIRALY, MARIANNA, DATTA, DEEPSHIKHA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein include methods, compositions, and kits suitable for use in preventing and treating a neurological disease or disorder. The method can comprise administering to a subject in need thereof a composition comprising conditionally activatable small interfering RNA (siRNA) complexes. L'invention concerne des méthodes, des compositions et des kits appropriés pour une utilisation dans la prévention et le traitement d'une maladie ou d'un trouble neurologique. La méthode peut comprendre l'administration à un sujet qui en a besoin d'une composition comprenant des complexes d'ARN interférent (ARNi) à activation conditionnelle.