IMMUNOGENIC CONSTRUCTS AND VACCINES FOR USE IN THE PROPHYLACTIC AND THERAPEUTIC TREATMENT OF DISEASES CAUSED BY SARS-COV-2

This invention relates to immunogenic constructs, such as polynucleotides, polypeptides and multimeric proteins and to antigenic units and to pharmaceutical compositions/vaccines comprising such immunogenic constructs or antigenic units, which are useful for the prophylactic and therapeutic treatmen...

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Bibliographische Detailangaben
Hauptverfasser: EBERT, PETER, NORHEIM, GUNNSTEIN, SEKELJA, MONIKA, OSBORNE, EDWARD, KLINGER, MARK, SNYDER, THOMAS, FREDRIKSEN, AGNETE, STUBSRUD, ELISABETH
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:This invention relates to immunogenic constructs, such as polynucleotides, polypeptides and multimeric proteins and to antigenic units and to pharmaceutical compositions/vaccines comprising such immunogenic constructs or antigenic units, which are useful for the prophylactic and therapeutic treatment of diseases caused by severe acute respiratory coronavirus 2 (SARS-CoV-2), as well as methods for producing and using the immunogenic constructs, antigenic units and pharmaceutical compositions/vaccines. La présente invention concerne des constructions immunogènes, telles que des polynucléotides, des polypeptides et des protéines multimères et des unités antigéniques ainsi que des compositions/vaccins pharmaceutiques contenant de telles constructions immunogènes ou unités antigéniques, qui sont utiles pour le traitement prophylactique et thérapeutique de maladies provoquées par un coronavirus 2 du syndrome respiratoire aigu sévère (SARS-COV-2), ainsi que des méthodes de production et d'utilisation des constructions immunogènes, des unités antigéniques et des compositions/vaccins pharmaceutiques.