EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF
Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention c...
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creator | TURNBULL, WILLIAM LESLIE JARAMILLO, MARIA WU, CUNLE DUFFY, IAN R MARCIL, ANNE METCALF, JULIE GRINSHTEIN, NATALIE SULEA, TRAIAN MORENO, MARIA |
description | Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions.
L'invention concerne des composés, par exemple des radio-immunoconjugués comprenant une fraction chélatante ou un complexe métallique de celle-ci, un lieur et une fraction de ciblage de EGFRvIII. L'invention concerne également des compositions pharmaceutiques de ces composés et des méthodes de traitement d'affections, par exemple le cancer, à l'aide de telles compositions pharmaceutiques. |
format | Patent |
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subjects | HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
title | EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF |
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