EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF

Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention c...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: TURNBULL, WILLIAM LESLIE, JARAMILLO, MARIA, WU, CUNLE, DUFFY, IAN R, MARCIL, ANNE, METCALF, JULIE, GRINSHTEIN, NATALIE, SULEA, TRAIAN, MORENO, MARIA
Format: Patent
Sprache:eng ; fre
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
container_end_page
container_issue
container_start_page
container_title
container_volume
creator TURNBULL, WILLIAM LESLIE
JARAMILLO, MARIA
WU, CUNLE
DUFFY, IAN R
MARCIL, ANNE
METCALF, JULIE
GRINSHTEIN, NATALIE
SULEA, TRAIAN
MORENO, MARIA
description Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention concerne des composés, par exemple des radio-immunoconjugués comprenant une fraction chélatante ou un complexe métallique de celle-ci, un lieur et une fraction de ciblage de EGFRvIII. L'invention concerne également des compositions pharmaceutiques de ces composés et des méthodes de traitement d'affections, par exemple le cancer, à l'aide de telles compositions pharmaceutiques.
format Patent
fullrecord <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA3233733A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA3233733A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA3233733A13</originalsourceid><addsrcrecordid>eNrjZNBxdXcLCvP09NQNcQxydw1xdVFw9vcN8A_1cwlWcPRzUQgNdg1WCPFwDXL1d-NhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHOjsZGxsbmxsaOhsZEKAEAVnkksw</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF</title><source>esp@cenet</source><creator>TURNBULL, WILLIAM LESLIE ; JARAMILLO, MARIA ; WU, CUNLE ; DUFFY, IAN R ; MARCIL, ANNE ; METCALF, JULIE ; GRINSHTEIN, NATALIE ; SULEA, TRAIAN ; MORENO, MARIA</creator><creatorcontrib>TURNBULL, WILLIAM LESLIE ; JARAMILLO, MARIA ; WU, CUNLE ; DUFFY, IAN R ; MARCIL, ANNE ; METCALF, JULIE ; GRINSHTEIN, NATALIE ; SULEA, TRAIAN ; MORENO, MARIA</creatorcontrib><description>Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention concerne des composés, par exemple des radio-immunoconjugués comprenant une fraction chélatante ou un complexe métallique de celle-ci, un lieur et une fraction de ciblage de EGFRvIII. L'invention concerne également des compositions pharmaceutiques de ces composés et des méthodes de traitement d'affections, par exemple le cancer, à l'aide de telles compositions pharmaceutiques.</description><language>eng ; fre</language><subject>HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230406&amp;DB=EPODOC&amp;CC=CA&amp;NR=3233733A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25564,76547</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&amp;date=20230406&amp;DB=EPODOC&amp;CC=CA&amp;NR=3233733A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>TURNBULL, WILLIAM LESLIE</creatorcontrib><creatorcontrib>JARAMILLO, MARIA</creatorcontrib><creatorcontrib>WU, CUNLE</creatorcontrib><creatorcontrib>DUFFY, IAN R</creatorcontrib><creatorcontrib>MARCIL, ANNE</creatorcontrib><creatorcontrib>METCALF, JULIE</creatorcontrib><creatorcontrib>GRINSHTEIN, NATALIE</creatorcontrib><creatorcontrib>SULEA, TRAIAN</creatorcontrib><creatorcontrib>MORENO, MARIA</creatorcontrib><title>EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF</title><description>Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention concerne des composés, par exemple des radio-immunoconjugués comprenant une fraction chélatante ou un complexe métallique de celle-ci, un lieur et une fraction de ciblage de EGFRvIII. L'invention concerne également des compositions pharmaceutiques de ces composés et des méthodes de traitement d'affections, par exemple le cancer, à l'aide de telles compositions pharmaceutiques.</description><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2023</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNrjZNBxdXcLCvP09NQNcQxydw1xdVFw9vcN8A_1cwlWcPRzUQgNdg1WCPFwDXL1d-NhYE1LzClO5YXS3AwKbq4hzh66qQX58anFBYnJqXmpJfHOjsZGxsbmxsaOhsZEKAEAVnkksw</recordid><startdate>20230406</startdate><enddate>20230406</enddate><creator>TURNBULL, WILLIAM LESLIE</creator><creator>JARAMILLO, MARIA</creator><creator>WU, CUNLE</creator><creator>DUFFY, IAN R</creator><creator>MARCIL, ANNE</creator><creator>METCALF, JULIE</creator><creator>GRINSHTEIN, NATALIE</creator><creator>SULEA, TRAIAN</creator><creator>MORENO, MARIA</creator><scope>EVB</scope></search><sort><creationdate>20230406</creationdate><title>EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF</title><author>TURNBULL, WILLIAM LESLIE ; JARAMILLO, MARIA ; WU, CUNLE ; DUFFY, IAN R ; MARCIL, ANNE ; METCALF, JULIE ; GRINSHTEIN, NATALIE ; SULEA, TRAIAN ; MORENO, MARIA</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3233733A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2023</creationdate><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>TURNBULL, WILLIAM LESLIE</creatorcontrib><creatorcontrib>JARAMILLO, MARIA</creatorcontrib><creatorcontrib>WU, CUNLE</creatorcontrib><creatorcontrib>DUFFY, IAN R</creatorcontrib><creatorcontrib>MARCIL, ANNE</creatorcontrib><creatorcontrib>METCALF, JULIE</creatorcontrib><creatorcontrib>GRINSHTEIN, NATALIE</creatorcontrib><creatorcontrib>SULEA, TRAIAN</creatorcontrib><creatorcontrib>MORENO, MARIA</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>TURNBULL, WILLIAM LESLIE</au><au>JARAMILLO, MARIA</au><au>WU, CUNLE</au><au>DUFFY, IAN R</au><au>MARCIL, ANNE</au><au>METCALF, JULIE</au><au>GRINSHTEIN, NATALIE</au><au>SULEA, TRAIAN</au><au>MORENO, MARIA</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF</title><date>2023-04-06</date><risdate>2023</risdate><abstract>Compounds, e.g., radioimmunoconjuguates including a chelating moiety or a metal complex thereof, a linker, and an EGFRvIII targeting moiety. Pharmaceutical compositions of such compounds and methods of treatment for conditions, e.g., cancer, using such pharmaceutical compositions. L'invention concerne des composés, par exemple des radio-immunoconjugués comprenant une fraction chélatante ou un complexe métallique de celle-ci, un lieur et une fraction de ciblage de EGFRvIII. L'invention concerne également des compositions pharmaceutiques de ces composés et des méthodes de traitement d'affections, par exemple le cancer, à l'aide de telles compositions pharmaceutiques.</abstract><oa>free_for_read</oa></addata></record>
fulltext fulltext_linktorsrc
identifier
ispartof
issn
language eng ; fre
recordid cdi_epo_espacenet_CA3233733A1
source esp@cenet
subjects HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
title EGFRVIII-TARGETED COMPOUNDS AND USES THEREOF
url https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2024-12-24T21%3A17%3A46IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=TURNBULL,%20WILLIAM%20LESLIE&rft.date=2023-04-06&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA3233733A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true