IL1RAP ANTIBODIES AND USES THEREOF

IL1RAP ANTIBODIES AND USES THEREOF

The present disclosure provides isolated anti-IL1RAP antibodies comprising the complementarity determining regions (CDRs) amino acid sequences, as disclosed herein. The disclosure further provides specific variable heavy chain and variable light chain amino acid sequences of these isolated anti-IL1R...

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Hauptverfasser: CHEN, JIAHAO, BIDERMAN, LYNN, NAKAYAMA, YASUMI, DUEY, DANA YEN MEI, LIPPINCOTT, JOHN ANDREW, ROOPNARIANE, ADRIANA PERMAUL, DOYLE, PATRICK JAMES, LORENZ, IVO C, GUERNAH, ILHEM, BENARD, LUMIE MARIE JOSEPHINE, BUGAJ-GAWEDA, BOZENA, KAROULIA, ZOI, CARPENITO, CARMINE
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present disclosure provides isolated anti-IL1RAP antibodies comprising the complementarity determining regions (CDRs) amino acid sequences, as disclosed herein. The disclosure further provides specific variable heavy chain and variable light chain amino acid sequences of these isolated anti-IL1RAP antibodies. The anti-IL1RAP antibodies target downstream IL1RAP activity appear useful for treating diseases such as cancer.