LIPIDATED PEPTIDE INHIBITORS OF INTERLEUKIN-23 RECEPTOR

The present invention relates to novel lipidated peptide inhibitors of the interleukin- 23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof., corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune...

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Hauptverfasser: ZHANG, JING, SOMANI, SANDEEP, DANIEL, JAMES, BRANCA, DANILA, TRAN, TRAN TRUNG, PATCH, RAYMOND J, BHANDARI, ASHOK, BARROS, STEPHANIE A, COSTANTE, ROBERTO, LOLLOBRIGIDA, MARTINA, DEL RIZZO, SONIA, BIANCHI, ELISABETTA, SUN, CHENGZAO, ROSOLIA, FEDERICA, RIEXINGER, DOUGLAS, HENDRICK, CHARLES, FREDERICK, BRIAN, NEELAMKAVIL, SANTHOSH
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Sprache:eng ; fre
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Zusammenfassung:The present invention relates to novel lipidated peptide inhibitors of the interleukin- 23 receptor (IL-23R) or pharmaceutically acceptable salts, solvates and/or other forms thereof., corresponding pharmaceutical compositions, methods and/or uses of the IL-23R inhibitors for treatment of autoimmune inflammation diseases and/or related disorders. Included are various, highly-customizable peptide sequences to be tailored to treat a broad range of ailments. La présente invention concerne de nouveaux inhibiteurs peptidiques lipidés du récepteur de l'interleukine-23 (IL-23R) ou des sels pharmaceutiquement acceptables, des solvates et/ou d'autres formes de ceux-ci, des compositions pharmaceutiques correspondantes, des procédés et/ou des utilisations des inhibiteurs de IL-23 R pour le traitement de maladies inflammatoires auto-immunes et/ou de troubles apparentés.