BISPECIFIC ANTI-CCL2 ANTIBODIES

The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases. La présente invention c...

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Bibliographische Detailangaben
Hauptverfasser:	HO, WEI SHIONG ADRIAN, SYDOW-ANDERSEN, JASMIN, FENG, SHU, BERTINETTI-LAPATKI, CRISTINA, GAN, SIOK WAN, GERTZ, MICHAEL, KACPRZYK, LUKASZ, GEORGES, GUY, LAM, RUNYI ADELINE, RUNZA, VALERIA, FISCHER, JENS
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to bispecific anti-CCL2 antibodies binding to two different epitopes on human CCL2, pharmaceutical compositions thereof, their manufacture, and use as medicaments for the treatment of cancers, inflammatory, autoimmune and ophthalmologic diseases. La présente invention concerne des anticorps anti-CCL2 bispécifiques se liant à deux épitopes différents sur le CCL2 humain, leurs compositions pharmaceutiques, leur fabrication et leur utilisation en tant que médicaments pour le traitement de cancers, de maladies inflammatoires, auto-immunes et ophtalmologiques.