VENETOCLAX DOSING REGIMENS FOR USE IN TREATING MYELODYSPLASTIC SYNDROMES IN COMBINATION WITH A CYP3A INHIBITOR AND AZACITIDINE

VENETOCLAX DOSING REGIMENS FOR USE IN TREATING MYELODYSPLASTIC SYNDROMES IN COMBINATION WITH A CYP3A INHIBITOR AND AZACITIDINE

The invention described herein relates to therapeutic dosing regimens comprising administering venetoclax in combination with azacitidine and a CYP3A inhibitor for treating myelodysplastic syndromes (MDS). L'invention concerne des régimes posologiques thérapeutiques comprenant l'administra...

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Bibliographische Detailangaben
Hauptverfasser: ZHA, JIUHONG, SALEM, AHMED, HAYSLIP, JOHN, KYE, STEVE H
Format: Patent
Sprache:eng ; fre
Schlagworte:
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Zusammenfassung:The invention described herein relates to therapeutic dosing regimens comprising administering venetoclax in combination with azacitidine and a CYP3A inhibitor for treating myelodysplastic syndromes (MDS). L'invention concerne des régimes posologiques thérapeutiques comprenant l'administration de vénétoclax en association avec de l'azacitidine et un inhibiteur de CYP3A pour le traitement de syndromes myélodysplasiques (SMD).