COMPOSITIONS AND METHODS FOR TREATING CHRONIC ACTIVE WHITE MATTER LESIONS / RADIOLOGICALLY ISOLATED SYNDROME

Provided herein are methods for administering disease-modifying antibody therapies to asymptomatic and/or early-stage multiple sclerosis patients, including Radiologically Isolated Syndrome patients, based on the identification and/or co-localization of slowly expanding lesions and paramagnetic rim...

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Bibliographische Detailangaben
1. Verfasser:	BELACHEW, SHIBESHIH MITIKU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are methods for administering disease-modifying antibody therapies to asymptomatic and/or early-stage multiple sclerosis patients, including Radiologically Isolated Syndrome patients, based on the identification and/or co-localization of slowly expanding lesions and paramagnetic rim lesions in magnetic resonance images from said patients. L'invention concerne des méthodes d'administration de thérapies par anticorps modifiant une maladie à des patients atteints de sclérose en plaques asymptomatiques et/ou précoces, y compris des patients atteints du syndrome radiologiquement isolé, sur la base de l'identification et/ou de la co-localisation de lésions à expansion lente et de lésions à rebord paramagnétique dans des images de résonance magnétique provenant desdits patients.