PROCESS FOR PREPARATION OF CABOZANTINIB

The present invention provides for novel amorphous solid dispersions of form of cabozantinib malate, and a pharmaceutically acceptable excipient and process for the preparation of cabozantinib malate. The invention also provides a novel crystalline polymorph of cabozantinib. La présente invention co...

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Hauptverfasser: KUMAR, NARASIMMAN, MATTI, LANKESWARARAO, DEVAIAH, VENU THIRUNELIMADA, BHAT, RAMAKRISHNA PARAMESHWAR, PATEL, PRATIK RAMESHCHANDRA, NAIR, RANJEET, CHETTY, JITHENDRABABU RAGHUNADHA
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention provides for novel amorphous solid dispersions of form of cabozantinib malate, and a pharmaceutically acceptable excipient and process for the preparation of cabozantinib malate. The invention also provides a novel crystalline polymorph of cabozantinib. La présente invention concerne de nouvelles dispersions solides amorphes de forme de malate de cabozantinib, et un excipient pharmaceutiquement acceptable et un procédé de préparation de malate de cabozantinib. L'invention concerne également un nouveau polymorphe cristallin de cabozantinib.