ANTIBODIES AGAINST INTEGRIN HETERODIMERS AND USES THEREOF

The disclosure provides antibodies that bind human ITGAv/B1 and methods of use thereof. In some aspects, the disclosure is directed to methods of treating a cancer in a subject, comprising administering to the subject an anti-ITGAv/B1 antibody. La divulgation concerne des anticorps qui se lient à l&...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: SIDHU, SACHDEV S, GALLO, EUGENIO, CARDARELLI, RODILIA, ADAMS, JARRETT J, BLAZER, LEVI LYNN, KELIL, ABDELLALI
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The disclosure provides antibodies that bind human ITGAv/B1 and methods of use thereof. In some aspects, the disclosure is directed to methods of treating a cancer in a subject, comprising administering to the subject an anti-ITGAv/B1 antibody. La divulgation concerne des anticorps qui se lient à l'ITGAv/B1 humain et des procédés d'utilisation de ceux-ci. Dans certains aspects, l'invention concerne des méthodes de traitement d'un cancer chez un sujet, comprenant l'administration au sujet d'un anticorps anti-ITGAv/B1.