MATERIALS AND METHODS FOR TARGETING REGULATORY T CELLS FOR ENHANCING IMMUNE SURVEILLANCE

MATERIALS AND METHODS FOR TARGETING REGULATORY T CELLS FOR ENHANCING IMMUNE SURVEILLANCE

A molecule comprising a first means of binding to a first antigen expressed on a regulatory T (Treg) cell, and a second means capable of binding to a second antigen expressed on the Treg cell, wherein the molecule is capable of inhibiting growth or proliferation of or depleting a Treg cell. L'i...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: GREWAL, IQBAL S, GANESAN, RAJKUMAR, DEES, SUNDEE, SINGH, SANJAYA
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:A molecule comprising a first means of binding to a first antigen expressed on a regulatory T (Treg) cell, and a second means capable of binding to a second antigen expressed on the Treg cell, wherein the molecule is capable of inhibiting growth or proliferation of or depleting a Treg cell. L'invention concerne une molécule comprenant un premier moyen de liaison à un premier antigène exprimé sur un lymphocyte T régulateur (Treg) et un second moyen capable de se lier à un second antigène exprimé sur le lymphocyte Treg, la molécule étant capable d'inhiber la croissance ou la prolifération d'un lymphocyte Treg ou d'appauvrir un lymphocyte Treg.