USE OF AKR1C3-ACTIVATED COMPOUND

Provided are the use of the compound 1-(3-(3-N,N-dimethylaminocarbonyl)phenoxyl-4-mtrophenyl)-1-ethyl-N,N'-bis(ethylene)phosphoramidate, or a pharmaceutically acceptable salt, isotopic variant or solvate thereof in the manufacture of a medicament for treating cancer, and a composition which com...

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Bibliographische Detailangaben
Hauptverfasser:	CHEN, LU-TZU, LAI, MING-TAIN, MENG, FANYING, LI, WAN-FEN, QI, TIANYANG, WANG, CHUNUNG, DUAN, JIANXIN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are the use of the compound 1-(3-(3-N,N-dimethylaminocarbonyl)phenoxyl-4-mtrophenyl)-1-ethyl-N,N'-bis(ethylene)phosphoramidate, or a pharmaceutically acceptable salt, isotopic variant or solvate thereof in the manufacture of a medicament for treating cancer, and a composition which comprises the above compound and at least one anti-cancer drug. L'invention concerne l'utilisation du composé 1-(3-(3-N,N-diméthylaminocarbonyl)phénoxyl-4-nitrophényl)-1-éthyl-N,N'-bis(éthylène)phosphoramidate, ou d'un sel pharmaceutiquement acceptable, d'un variant isotopique ou d'un solvate de celui-ci dans la fabrication d'un médicament pour le traitement du cancer, et une composition qui comprend le composé ci-dessus et au moins un médicament anticancéreux.