PHARMACEUTICAL COMPOUNDS

This invention relates to compounds that are agonists of the muscarinic M1 and M4 receptor and which are useful in the treatment of diseases mediated by the muscarinic M1 and/or M4 receptors. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compo...

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Bibliographische Detailangaben
Hauptverfasser:	FIELDHOUSE, CHARLOTTE, CONGREVE, MILES STUART
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	This invention relates to compounds that are agonists of the muscarinic M1 and M4 receptor and which are useful in the treatment of diseases mediated by the muscarinic M1 and/or M4 receptors. Also provided are pharmaceutical compositions containing the compounds and the therapeutic uses of the compounds. Compounds provided are of formula (1): and salts thereof. La présente invention concerne des composés qui sont des agonistes des récepteurs muscariniques M1 et M4 et qui sont utiles dans le traitement de maladies médiées par les récepteurs muscariniques M1 et/ou M4. L'invention concerne également des compositions pharmaceutiques contenant les composés et les utilisations thérapeutiques desdits composés. L'invention concerne des composés de formule (1) : et des sels de ceux-ci.