N-BENZYL-ALPHA-AMINOAMIDES AS ANAPHASE-PROMOTING COMPLEX/CYCLOSOME (APC/C) INHIBITORS

The invention relates to inhibitors of anaphase promoting complex/cyclosome (APC/C) function of formula (I), wherein the meaning for R1 and R2 is as disclosed in the description. These compounds are useful in the treatment of cancer, particularly, in the treatment of breast cancer. L'invention...

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Bibliographische Detailangaben
Hauptverfasser:	BASTIDA CODINA, AGATHA, CURTIS, NATALIE LAURA, BENITO ARENAS, RAUL, BOLANOS-GARCIA, VICTOR M
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	The invention relates to inhibitors of anaphase promoting complex/cyclosome (APC/C) function of formula (I), wherein the meaning for R1 and R2 is as disclosed in the description. These compounds are useful in the treatment of cancer, particularly, in the treatment of breast cancer. L'invention concerne des inhibiteurs de la fonction du complexe de promotion de l'anaphase/cyclosome (APC/C) représentés par la formule (I), la signification de R1 et R2 étant telle que divulguée dans la description. Ces composés sont utiles dans le traitement du cancer, en particulier, dans le traitement du cancer du sein.