VARIANT ADENO-ASSOCIATED VIRUS (AAV)CAPSID POLYPEPTIDES AND GENE THERAPEUTICS THEREOF FOR TREATMENT OF HEARING LOSS

Described herein are variant adeno-associated virus (AAV) capsid polypeptides and gene therapeutics thereof for use in the treatment or prevention of hearing loss. L'invention concerne des polypeptides de capside de virus adéno-associé (AAV) variant et des agents de thérapie génique corresponda...

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Hauptverfasser:	TIMMERS, ADRIAN M, JACQUES, BONNIE E, URIBE, PHILLIP M, FOSTER, ALAN C, PENNOCK, STEVEN, MATHUR, PRANAV DINESH, SHEARMAN, MARK, BARTOLOME, CHRISTOPHER, SZOBOTA, STEPHANIE, PIU, FABRICE, WANG, XIAOBO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Described herein are variant adeno-associated virus (AAV) capsid polypeptides and gene therapeutics thereof for use in the treatment or prevention of hearing loss. L'invention concerne des polypeptides de capside de virus adéno-associé (AAV) variant et des agents de thérapie génique correspondants destinés à être utilisés dans le traitement ou la prévention de la perte auditive.