METHODS OF TREATING TUMORS

The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La divulgation concerne des compo...

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Bibliographische Detailangaben
Hauptverfasser: ZHAO, XIAOCHEN, HABY, THOMAS ARTHUR, KHOSSRAVI, MEHRNAZ, ROY, AMIT, MURTHY, BINDU PURNIMA, ARAS, URVI ASHISH, MANTRI, RAO VENKATRAMANA, VEZINA, HEATHER ELIZABETH, HUANG, MASANO, SANGHAVI, KINJAL, HART, SCOTT AARON, BELLO, AKINTUNDE
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The disclosure provides pharmaceutical compositions comprising an anti-PD-1 antibody or an anti-PD-LI antibody formulated for subcutaneous delivery, wherein the pharmaceutical compositions further comprise an endoglycosidase hydrolase enzyme such as a hyaluronidase. La divulgation concerne des compositions pharmaceutiques comprenant un anticorps anti-PD-1 ou un anticorps anti-PD-L1 formulé pour une administration sous-cutanée, les compositions pharmaceutiques comprenant en outre une enzyme endoglycosidase hydrolase telle qu'une hyaluronidase.