CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF
CFTR modulator compounds and compositions including said compounds are provided. The present disclosure also provides PDE4 inhibiting compounds and compositions including said compounds. Also provided are methods of using said compounds and compositions for modulating CFTR, methods for treating an e...
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| creator | KIM, JUNGHO LIM, DAMI JEONG, ILJI AN, KYUNG MI LEE, MYONGJAE KIM, KYEONG-A LEE, JUNG WOO YOON, JONGMIN LEE, SEOLHEE RYU, JAEEUN KWON, JINSUN JUN, YEARIN OH, CHANGMOK YOON, HONGCHUL LEE, JOOYUN LEE, JIN HEE SOHN, TE-IK KIM, GUNHEE PARK, JOONTAE |
| description | CFTR modulator compounds and compositions including said compounds are provided. The present disclosure also provides PDE4 inhibiting compounds and compositions including said compounds. Also provided are methods of using said compounds and compositions for modulating CFTR, methods for treating an eye disease or disorder and methods for treating CFTR-related indications. The present disclosure also provides methods of using said compounds and compositions for inhibiting PDE4, for treating an inflammatory disease or disorder and for treating other PDE4-related indications. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.
La divulgation concerne des composés modulateurs de CFTR et des compositions comprenant lesdits composés. La présente divulgation concerne également des composés inhibiteurs de PDE4 et des compositions comprenant lesdits composés. La divulgation concerne également des procédés d'utilisation desdits composés et compositions pour la modulation de CFTR, des procédés de taitement d'une maladie ou d'un trouble oculaire et des procédés de traitement d'indications liées au CFTR. La présente divulgation concerne également des procédés d'utilisation desdits composés et compositions pour inhiber PDE4, traiter une maladie ou un trouble inflammatoire et traiter d'autres indications liées à PDE4. L'invention concerne également des procédés de préparation desdits composés et compositions, ainsi que des précurseurs synthétiques desdits composés. |
| format | Patent |
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La divulgation concerne des composés modulateurs de CFTR et des compositions comprenant lesdits composés. La présente divulgation concerne également des composés inhibiteurs de PDE4 et des compositions comprenant lesdits composés. La divulgation concerne également des procédés d'utilisation desdits composés et compositions pour la modulation de CFTR, des procédés de taitement d'une maladie ou d'un trouble oculaire et des procédés de traitement d'indications liées au CFTR. La présente divulgation concerne également des procédés d'utilisation desdits composés et compositions pour inhiber PDE4, traiter une maladie ou un trouble inflammatoire et traiter d'autres indications liées à PDE4. L'invention concerne également des procédés de préparation desdits composés et compositions, ainsi que des précurseurs synthétiques desdits composés.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2022</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220428&DB=EPODOC&CC=CA&NR=3196061A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76290</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20220428&DB=EPODOC&CC=CA&NR=3196061A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>KIM, JUNGHO</creatorcontrib><creatorcontrib>LIM, DAMI</creatorcontrib><creatorcontrib>JEONG, ILJI</creatorcontrib><creatorcontrib>AN, KYUNG MI</creatorcontrib><creatorcontrib>LEE, MYONGJAE</creatorcontrib><creatorcontrib>KIM, KYEONG-A</creatorcontrib><creatorcontrib>LEE, JUNG WOO</creatorcontrib><creatorcontrib>YOON, JONGMIN</creatorcontrib><creatorcontrib>LEE, SEOLHEE</creatorcontrib><creatorcontrib>RYU, JAEEUN</creatorcontrib><creatorcontrib>KWON, JINSUN</creatorcontrib><creatorcontrib>JUN, YEARIN</creatorcontrib><creatorcontrib>OH, CHANGMOK</creatorcontrib><creatorcontrib>YOON, HONGCHUL</creatorcontrib><creatorcontrib>LEE, JOOYUN</creatorcontrib><creatorcontrib>LEE, JIN HEE</creatorcontrib><creatorcontrib>SOHN, TE-IK</creatorcontrib><creatorcontrib>KIM, GUNHEE</creatorcontrib><creatorcontrib>PARK, JOONTAE</creatorcontrib><title>CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF</title><description>CFTR modulator compounds and compositions including said compounds are provided. The present disclosure also provides PDE4 inhibiting compounds and compositions including said compounds. Also provided are methods of using said compounds and compositions for modulating CFTR, methods for treating an eye disease or disorder and methods for treating CFTR-related indications. The present disclosure also provides methods of using said compounds and compositions for inhibiting PDE4, for treating an inflammatory disease or disorder and for treating other PDE4-related indications. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.
La divulgation concerne des composés modulateurs de CFTR et des compositions comprenant lesdits composés. La présente divulgation concerne également des composés inhibiteurs de PDE4 et des compositions comprenant lesdits composés. La divulgation concerne également des procédés d'utilisation desdits composés et compositions pour la modulation de CFTR, des procédés de taitement d'une maladie ou d'un trouble oculaire et des procédés de traitement d'indications liées au CFTR. La présente divulgation concerne également des procédés d'utilisation desdits composés et compositions pour inhiber PDE4, traiter une maladie ou un trouble inflammatoire et traiter d'autres indications liées à PDE4. 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The present disclosure also provides PDE4 inhibiting compounds and compositions including said compounds. Also provided are methods of using said compounds and compositions for modulating CFTR, methods for treating an eye disease or disorder and methods for treating CFTR-related indications. The present disclosure also provides methods of using said compounds and compositions for inhibiting PDE4, for treating an inflammatory disease or disorder and for treating other PDE4-related indications. Also provided are methods of preparing said compounds and compositions, and synthetic precursors of said compounds.
La divulgation concerne des composés modulateurs de CFTR et des compositions comprenant lesdits composés. La présente divulgation concerne également des composés inhibiteurs de PDE4 et des compositions comprenant lesdits composés. La divulgation concerne également des procédés d'utilisation desdits composés et compositions pour la modulation de CFTR, des procédés de taitement d'une maladie ou d'un trouble oculaire et des procédés de traitement d'indications liées au CFTR. La présente divulgation concerne également des procédés d'utilisation desdits composés et compositions pour inhiber PDE4, traiter une maladie ou un trouble inflammatoire et traiter d'autres indications liées à PDE4. L'invention concerne également des procédés de préparation desdits composés et compositions, ainsi que des précurseurs synthétiques desdits composés.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | CFTR MODULATOR COMPOUNDS, COMPOSITIONS, AND USES THEREOF |
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