CYCLIN-DEPENDENT KINASE 7 (CDK7) NON-COVALENT INHIBITORS

The invention relates to pharmaceutical compounds of formula (I) and pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds as inhibitors of cyclin-dependent kinase 7 (CDK7) and to their use in the treatment of disea...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser:	MEVELLEC, LAURENCE ANNE, COUPA EP. DESCAMPS, SOPHIE, LIGNY, YANNICK AIME EDDY, ADELINET, CHRISTOPHE DENIS PASCAL, MEYER, CHRISTOPHE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to pharmaceutical compounds of formula (I) and pharmaceutical compositions comprising said compounds, to processes for the preparation of said compounds and to the use of said compounds as inhibitors of cyclin-dependent kinase 7 (CDK7) and to their use in the treatment of diseases, e.g. cancer. L'invention concerne des composés pharmaceutiques de formule (I) et des compositions pharmaceutiques comprenant lesdits composés, des procédés pour la préparation desdits composés et l'utilisation desdits composés en tant qu'inhibiteurs de la kinase cycline-dépendante 7 (CDK7) et leur utilisation dans le traitement de maladies, par exemple le cancer.