TRIAZINE COMPOUND SALT, CRYSTAL FORM THEREOF, AND PRODUCTION METHOD THEREFOR
The present invention provides a salt of a triazine compound which has an inhibitory action against aldosterone synthase and is useful as a drug, and especially as a drug for preventing or treating primary aldosteronism and the like, a crystal thereof, and a method for producing the same. Specifical...
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Zusammenfassung: | The present invention provides a salt of a triazine compound which has an inhibitory action against aldosterone synthase and is useful as a drug, and especially as a drug for preventing or treating primary aldosteronism and the like, a crystal thereof, and a method for producing the same. Specifically, the present invention provides a pharmaceutically acceptable salt of 3-[4-[[trans-4-(acetamino)cyclohexyl]carbamoylmethyl]piperazin-1-yl]-5-(p-tolyl)-1,2,4-triazine, wherein the salt is hydrobromide, sulfate, succinate, or tosilate, and the like.
La présente invention concerne un sel de composé triazine qui a un effet inhibiteur de l'aldostérone synthase et est utile en tant que médicament, en particulier, un agent pour prévenir ou traiter l'aldostéronisme primaire et analogue, un cristal, et son procédé de production. Spécifiquement, la présente invention concerne un sel pharmaceutiquement acceptable de 3-[4-[[trans-4-(acétamino)cyclohexyl]carbamoyl méthyl]pipérazine-1-yl]-5-(p-tolyl) -1,2,4-triazine, le sel étant un bromhydrate, un sulfate, un succinate ou un tosylate. |
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