ANTIBODIES AGAINST ILT2 AND USE THEREOF

The present disclosure provides monoclonal anti-ILT2 antibodies or antigen-binding fragments thereof, as well as pharmaceutical compositions comprising the same and methods of producing the same. Also provided are methods of treating cancer using the antibodies or compositions of the present disclos...

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Bibliographische Detailangaben
Hauptverfasser:	MANDEL, ILANA, GOLDSHTEIN, ILANA, SAPIR, YAIR, BEN-MOSHE, TEHILA, HAVES ZIV, DANA, PERETZ, TSURI, SHULMAN, AVIDOR, ALISHEKEVITZOR, HAKIM, MOTTI, FRIDMAN-DROR, ANNA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present disclosure provides monoclonal anti-ILT2 antibodies or antigen-binding fragments thereof, as well as pharmaceutical compositions comprising the same and methods of producing the same. Also provided are methods of treating cancer using the antibodies or compositions of the present disclosure. Methods of patient selection are also provided. La présente invention concerne des anticorps monoclonaux anti-ILT2 ou des fragments de liaison à l'antigène de ceux-ci, ainsi que des compositions pharmaceutiques les comprenant et des procédés de production de ceux-ci. L'invention concerne également des procédés de traitement du cancer à l'aide des anticorps ou des compositions de la présente invention. L'invention concerne également des procédés de sélection de patient.