FUNCTIONAL SCREENING USING DROPLET-BASED MICROFLUIDICS

Provided is a droplet-based microfluidics platform for functional screening of interacting molecules. The platform is particularly useful for high throughput screening of interacting proteins, such as antibodies or engineered cytokines, which trigger a detectable downstream signaling event. L'i...

Ausführliche Beschreibung

Gespeichert in:

Bibliographische Detailangaben
Hauptverfasser:	HUANG, MENGSHI, SCHWEIZER, LIANG, ZHANG, HONGKAI, SHEN, BINGQING, JIN, RUINA, WANG, YUAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMBINATORIAL CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS SPIRITS TESTING VINEGAR WINE
Online-Zugang:	Volltext bestellen
Tags:	Tag hinzufügen Keine Tags, Fügen Sie den ersten Tag hinzu!

Beschreibung
Zusammenfassung:	Provided is a droplet-based microfluidics platform for functional screening of interacting molecules. The platform is particularly useful for high throughput screening of interacting proteins, such as antibodies or engineered cytokines, which trigger a detectable downstream signaling event. L'invention concerne une plateforme microfluidique à gouttelettes pour le criblage fonctionnel de molécules interactives. La plateforme est particulièrement utile pour le criblage à haut rendement de protéines en interaction, tels que des anticorps ou des cytokines modifiées, qui déclenchent un événement de signalisation en aval détectable.