METHODS FOR THE USE OF A PD-1 X CTLA-4 BISPECIFIC MOLECULE

The present invention is directed in part to dosing regimens for administering a PD-1 x CTLA- 4 bispecific molecule for the treatment of cancer, and other conditions. The invention is directed in part to the use of such molecules, and to the use of pharmaceutical compositions and pharmaceutical kits...

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Bibliographische Detailangaben
Hauptverfasser: WIGGINTON, JON MARC, SUMROW, BRADLEY JAMES, BONVINI, EZIO, SHARMA, SHARAD, BEREZHNOY, ALEXEY YEVGENYEVICH
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:The present invention is directed in part to dosing regimens for administering a PD-1 x CTLA- 4 bispecific molecule for the treatment of cancer, and other conditions. The invention is directed in part to the use of such molecules, and to the use of pharmaceutical compositions and pharmaceutical kits that contain such molecules and that facilitate the use of such dosing regimens in the treatment of cancer or to stimulate immune cells. La présente invention concerne en partie des schémas posologiques pour l'administration d'une molécule bispécifique PD-1 x CTLA-4 pour le traitement du cancer, et d'autres affections. L'invention concerne en partie l'utilisation de telles molécules, et l'utilisation de compositions pharmaceutiques et de kits pharmaceutiques qui contiennent de telles molécules et qui facilitent l'utilisation de tels schémas posologiques pour le traitement du cancer ou pour stimuler des cellules immunitaires.