CASEIN KINASE 1 DELTA MODULATORS

A compound of Formula (I), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with casein kinase 1 delta (CSNK1D) modulation, such as those associated with mood/psychiatric...

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Bibliographische Detailangaben
Hauptverfasser:	WU, DONGPEI, PATRICK, KELSEY, SWIFT, ELIZABETH, HANNA, LUKE EDWARD, PREVILLE, CATHY, SHIREMAN, BROCK T, MCCARVER, STEFAN, LEBOLD, TERRY PATRICK, SEIERSTAD, MARK, SAMANT, ANDREW V
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	A compound of Formula (I), pharmaceutical compositions containing them, methods of making them, and methods of using them including methods for treating disease states, disorders, and conditions associated with casein kinase 1 delta (CSNK1D) modulation, such as those associated with mood/psychiatric disorders, neurodegenerative diseases, cancers, addiction and substance abuse disorders, pain, and metabolic diseases.Wherein R1, R2, R3, and R4, are defined herein. L'invention concerne un composé de formule (I), des compositions pharmaceutiques le contenant, leurs procédés de fabrication, et leurs procédés d'utilisation incluant des méthodes de traitement d'états pathologiques, de troubles et d'états associés à la modulation de la caséine kinase 1 delta (CSNK1D), tels que ceux associés à des troubles de l'humeur/psychiatriques, des maladies neurodégénératives, des cancers, l'accoutumance et les troubles liés à l'abus de substances, la douleur, et des maladies métaboliques. R1, R2, R3 et R4 sont tels que définis dans la description.