ANTIGEN BINDING PROTEIN

Provided herein are antigen binding proteins that specifically bind to BMP1, TLL1 and/or TLL2. Also provided are pharmaceutical compositions containing the antigen binding proteins. The antigen binding proteins and pharmaceutical compositions described herein can be used to treat diseases associated...

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Bibliographische Detailangaben
Hauptverfasser:	ZHANG, JIAN, HARPEL, MARK R, CLARKSON, JANE ELIZABETH, HARRIS, CAROL A, DIMECH, CAROLINE J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	Provided herein are antigen binding proteins that specifically bind to BMP1, TLL1 and/or TLL2. Also provided are pharmaceutical compositions containing the antigen binding proteins. The antigen binding proteins and pharmaceutical compositions described herein can be used to treat diseases associated with fibrotic conditions or disorders as well as to promote muscle growth and improve muscle function. L'invention concerne des protéines de liaison à l'antigène qui se lient spécifiquement à BMP1, TLL1 et/ou TLL2. L'invention concerne également des compositions pharmaceutiques contenant les protéines de liaison à l'antigène. Les protéines de liaison à l'antigène et les compositions pharmaceutiques décrites ici peuvent être utilisées pour traiter des maladies associées à des états ou troubles fibrotiques, ainsi que pour favoriser la croissance musculaire et améliorer la fonction musculaire.