POLYCYCLIC CAP-DEPENDENT ENDONUCLEASE INHIBITORS FOR TREATING OR PREVENTING INFLUENZA

The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing influenza. The compounds are cap-dependent endonuclease inhibitors. La présente invention concerne un compos...

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Bibliographische Detailangaben
Hauptverfasser:	ZHAO, KAKE, BENNETT, FRANK, PLOTKIN, MICHAEL A, DE LERA RUIZ, MANUEL, CROWLEY, BRENDAN M, EMBREY, MARK W, KIM, RONALD M, FELLS, JAMES, ZHANG, YONGLIAN, GUO, LIANGQIN, SHURTLEFF, VALERIE W, LO, MICHAEL MANU, CHOBANIAN, HARRY R, MORRIELLO, GREGORI J, MCCAULEY, JOHN A, SU, HUA, DEJESUS, REYNALDA KEH
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention provides a compound of Formula (I) and pharmaceutical compositions comprising one or more said compounds, and methods for using said compounds for treating or preventing influenza. The compounds are cap-dependent endonuclease inhibitors. La présente invention concerne un composé de formule (I) et des compositions pharmaceutiques comprenant un ou plusieurs desdits composés, ainsi que des procédés d'utilisation desdits composés pour le traitement ou la prévention de la grippe. Les composés sont des inhibiteurs de l'endonucléase dépendante de la coiffe.