QUINAZOLINE DERIVATIVES USEFUL AS SELECTIVE HDAC6 INHIBITORS

Provided herein is a compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) and methods of using the compounds, e.g., in the treatment of neuropathy-re...

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Bibliographische Detailangaben
Hauptverfasser:	CHANG, HSIN-YI, HO, YI-HSUN, HUNG, PEI-YUN, JAGTAP, AJIT DHANANJAY, YU, CHAO-WU
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein is a compound of Formula (I): or a pharmaceutically acceptable salt thereof, wherein the variables are defined herein. Also provided herein are pharmaceutical compositions comprising a compound of Formula (I) and methods of using the compounds, e.g., in the treatment of neuropathy-related disorders and fibrotic diseases. L'invention concerne un composé de formule (I) : ou un sel pharmaceutiquement acceptable de celui-ci, les variables étant définies dans la description. L'invention concerne également des compositions pharmaceutiques comprenant un composé de formule (I) et des procédés d'utilisation des composés, par exemple, dans le traitement de troubles liés à la neuropathie et de maladies fibrotiques.