ANTI-BETACELLULIN ANTIBODIES, FRAGMENTS THEREOF, AND MULTI-SPECIFIC BINDING MOLECULES

ANTI-BETACELLULIN ANTIBODIES, FRAGMENTS THEREOF, AND MULTI-SPECIFIC BINDING MOLECULES

The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BT...

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Bibliographische Detailangaben
Hauptverfasser: HAUBST, NICOLE, BIGELOW, CHAD ERIC, POOR, STEPHEN HENDRICK, CLARK, KIRK LEE, TOKSOZ, ENGIN, HANKS, SHAWN MICHAEL, IYER, GANESH RAJAN, STEFANIDAKIS, MICHAEL, QIU, YUBIN, TWAROG, MICHAEL ZBIGNIEW, ETEMAD-GILBERTSON, BIJAN ALEXANDRE, MOKER, NINA, NGUYEN, ANDREW ANH, CARRION, ANA MARIA, CHASTAIN, JAMES EDGAR, RANGASWAMY, NALINI VELAMUR, GHOSH, JOY GISPATI
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The present disclosure provides anti-BTC antibodies, methods of producing said antibodies, pharmaceutical compositions comprising said antibodies, and methods of using said antibodies. The present disclosure also provides multi-specific binding molecules, e.g., bispecific antibodies, comprising a BTC binding moiety and an anti-VEGF binding moiety. La présente invention concerne des anticorps anti-BTC, des procédés de production desdits anticorps, des compositions pharmaceutiques comprenant lesdits anticorps, et des méthodes d'utilisation desdits anticorps. La présente invention concerne également des molécules de liaison multi-spécifiques, par exemple des anticorps bispécifiques, comprenant une fraction de liaison à BTC et une fraction de liaison anti-VEGF.