METHOD FOR PRODUCING DECELLULARIZED BIOMATERIAL, DECELLULARIZED BIOMATERIAL AND USE THEREOF

The present patent application pertains to the field of tissue engineering. In particular, the application relates to a method for producing decellularized biomaterial from biological tissue, and also the decellularized biomaterial produced by said method comprising an extracellular matrix of biolog...

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Hauptverfasser:	REZENDE ROSA, ROBERTA, REGINA DA COSTA SILVA, JESSICA, BATISTA FERNANDES GASPARI, PAULA, MENDONCA RODRIGUES, CLAUDIA, CARVALHO BARBOSA, MATHEUS, RICARDO GOULART FILHO, LUIZ, DE SOUZA CASTRO FILICE, LETICIA, CAROLINE RESENDE CORREA, NATASSIA, SOUSA QUIRINO, LUDMILLA, PEIXOTO RODRIGUES, JESSICA, SANTOS PIMENTEL, LETICIA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The present patent application pertains to the field of tissue engineering. In particular, the application relates to a method for producing decellularized biomaterial from biological tissue, and also the decellularized biomaterial produced by said method comprising an extracellular matrix of biological origin. Specifically, said biological tissue is obtained from ocular connective tissue of animal or human origin. More specifically, the application relates to a method for producing decellularized biomaterial from animal sclera to produce biological scaffolds, prostheses and/or pathways for active substances (or combined with active substances), and also the biomaterial itself and the uses thereof as scaffolds, prostheses or substance pathways for systemic or localized release. La présente demande de brevet concerne le domaine de l'ingénierie tissulaire. En particulier, l'invention concerne un procédé de production de biomatériau décellularisé à partir de tissu biologique, ainsi que le biomatériau décellularisé produit au moyen dudit procédé, comprenant une matrice extracellulaire d'origine biologique. Ledit tissu biologique est notamment issu de tissu conjonctif oculaire d'origine animale ou humaine. Plus particulièrement, l'invention concerne un procédé de production de biomatériau décellularisé à partir de sclère animale pour la production d'un échafaudage biologique, d'une prothèse et/ou d'un support de substances actives (ou en combinaison avec des substances actives), ainsi que le biomatériau lui-même et ses utilisations comme échafaudages, prothèses ou supports de substances pour libération systémique ou localisée.