HIGH MOLECULAR WEIGHT HEPARIN COMPOSITIONS AND METHODS FOR DIAGNOSING, TREATING AND MONITORING EOSINOPHIL MEDIATED INFLAMMATORY DISEASES

Disclosed herein are compositions comprising high molecular weight heparin. The compositions comprise an effective amount of high molecular weight heparin having an average molecular weight from about 20 kDa to about 40 kDa and having a purity of at least 50%, and a pharmaceutically acceptable excip...

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Bibliographische Detailangaben
Hauptverfasser:	LEIFERMAN, KRISTIN M, ECKERT, DEBRA, SAFFARI, HEDIEH, CONDIE, RUSSELL MORRIS, PETERSON, KATHRYN A, GLEICH, GERALD J
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	Disclosed herein are compositions comprising high molecular weight heparin. The compositions comprise an effective amount of high molecular weight heparin having an average molecular weight from about 20 kDa to about 40 kDa and having a purity of at least 50%, and a pharmaceutically acceptable excipient. Disclosed herein are also methods of treating eosinophil- related inflammation in a subject. L'invention concerne des compositions comprenant de l'héparine de poids moléculaire élevé. Les compositions comprennent une quantité efficace d'héparine de poids moléculaire élevé ayant un poids moléculaire moyen d'environ 20 kDa à environ 40 kDa et ayant une pureté d'au moins 50 %, et un excipient pharmaceutiquement acceptable. L'invention concerne également des procédés de traitement d'une inflammation liée aux éosinophiles chez un sujet.