TREATMENT OF CANCER WITH CDK12/13 INHIBITORS

TREATMENT OF CANCER WITH CDK12/13 INHIBITORS

Provided herein are compositions and methods for the treatment of a triple-negative breast cancer, ovarian cancer and castration-resistant prostate cancer. Said compositions comprise CDK12/13 inhibitors. L'invention concerne des compositions et des méthodes pour le traitement d'un cancer d...

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Hauptverfasser: GARDINER, ELISABETH, ARNOLD, LEE D, TYHONAS, JOHN, TIMPLE, NOELITO, KANOUNI, TOUFIKE, MARTIN, ERIC, MURPHY, ERIC A
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
METALLURGY
ORGANIC CHEMISTRY
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Zusammenfassung:Provided herein are compositions and methods for the treatment of a triple-negative breast cancer, ovarian cancer and castration-resistant prostate cancer. Said compositions comprise CDK12/13 inhibitors. L'invention concerne des compositions et des méthodes pour le traitement d'un cancer du sein triple-négatif, du cancer de l'ovaire et du cancer de la prostate résistant à la castration. Lesdites compositions comprennent des inhibiteurs de CDK12/13.