ANTIBODIES AGAINST INTEGRIN ALPHA 11 BETA 1

The present disclosure includes antibodies that specifically bind integrin alpha 11 beta 1 (a11ß1), as well as methods of making and using such antibodies. In some embodiments, an anti-a11 p1 antibody, or antigen-binding fragment thereof, is a monoclonal antibody, or antigen-binding fragment thereof...

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Bibliographische Detailangaben
Hauptverfasser:	MEADOR, JAMES W. III, BENEDUCE, CHRISTOPHER, KURTAGIC, ELMA
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY ENZYMOLOGY FERMENTATION OR ENZYME-USING PROCESSES TO SYNTHESISE A DESIREDCHEMICAL COMPOUND OR COMPOSITION OR TO SEPARATE OPTICAL ISOMERSFROM A RACEMIC MIXTURE HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY MICROBIOLOGY MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present disclosure includes antibodies that specifically bind integrin alpha 11 beta 1 (a11ß1), as well as methods of making and using such antibodies. In some embodiments, an anti-a11 p1 antibody, or antigen-binding fragment thereof, is a monoclonal antibody, or antigen-binding fragment thereof. The present disclosure also provides use of such antibodies to treat fibrotic disorders and/or cancers. La présente divulgation concerne des anticorps qui se lient spécifiquement à l'intégrine alpha 11 bêta 1 (a11ß1), ainsi que des procédés de fabrication et d'utilisation de tels anticorps. Dans certains modes de réalisation, un anticorps anti-a11 p 1 ou son fragment de liaison d'anticorps, est un anticorps monoclonal ou un fragment de liaison d'anticorps de celui-ci. La présente invention porte aussi sur l'utilisation de ces anticorps pour traiter des troubles fibrotiques et/ou des cancers.