6-MEMBERED HETEROARYLAMINOSULFONAMIDES FOR TREATING DISEASES AND CONDITIONS MEDIATED BY DEFICIENT CFTR ACTIVITY

The invention relates to heteroaryl compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cy...

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Bibliographische Detailangaben
Hauptverfasser:	GAO, ZHONGLI, MUNSON, MARK, HURLBUT, GREGORY, LIAO, JUNKAI
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
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Beschreibung
Zusammenfassung:	The invention relates to heteroaryl compounds, pharmaceutically acceptable salts thereof, and pharmaceutical preparations thereof. Also described herein are compositions and the use of such compounds in methods of treating diseases and conditions mediated by deficient CFTR activity, in particular cystic fibrosis. L'invention concerne des composés hétéroaryles, des sels pharmaceutiquement acceptables de ceux-ci, et des préparations pharmaceutiques de ceux-ci. L'invention concerne également des compositions et l'utilisation de tels composés dans des procédés de traitement de maladies et d'états pathologiques médiés par une activité de CFTR déficiente, en particulier la fibrose kystique.