METHODS OF USING ANTI-CD79B IMMUNOCONJUGATES TO TREAT DIFFUSE LARGE B-CELL LYMPHOMA

Provided herein are methods of treating B-cell proliferative disorders (such as diffuse large B-cell lymphoma (DLBCL)) using immunoconjugates comprising anti-CD79b antibodies in combination with an anti-CD20 antibody (such as rituximab) and one or more chemotherapeutic agents (such as gemcitabine an...

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Bibliographische Detailangaben
Hauptverfasser:	HERNANDEZ MONTALVO, JUANA ELVA, HIRATA, JAMIE HARUE, QAYUM, NASEER UL DIN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PEPTIDES PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are methods of treating B-cell proliferative disorders (such as diffuse large B-cell lymphoma (DLBCL)) using immunoconjugates comprising anti-CD79b antibodies in combination with an anti-CD20 antibody (such as rituximab) and one or more chemotherapeutic agents (such as gemcitabine and oxaliplatin). L'invention concerne des méthodes de traitement de troubles prolifératifs des lymphocytes B (tels que le lymphome diffus à grandes cellules B (DLBCL)) en utilisant des immunoconjugués comprenant des anticorps anti-CD79b en combinaison avec un anticorps anti-CD20 (tel que le rituximab) ainsi qu'un ou plusieurs agents de chimiothérapie (tels que la gemcitabine et l'oxaliplatine).