NEW TREATMENTS INVOLVING MIRNA-193A

The invention relates to the use ofmiRNA-193a for regulating gene expression, particularly it relates to the use of miRNA-193a as a PTEN agonist. This allows the advantageous treatment of PTEN- deficient cancers. The invention further relates to compositions comprising the miRNA for use as a PTEN ag...

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Bibliographische Detailangaben
Hauptverfasser:	VAN DEN BOSCH, MARION TINA JOLIEN, DE GUNST, MATHEUS MARIA, VAN PINXTEREN, LAURENS ADRIANUS HENDRICUS, YAHYANEJAD, SANAZ, SCHAAPVELD, ROELAND QUIRINUS JOZEF, ALEMDEHY, MIR FARSHID, JANICOT, MICHEL, TELFORD, BRYONY JANE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS THEREOF CULTURE MEDIA ENZYMOLOGY METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS VINEGAR WINE
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Beschreibung
Zusammenfassung:	The invention relates to the use ofmiRNA-193a for regulating gene expression, particularly it relates to the use of miRNA-193a as a PTEN agonist. This allows the advantageous treatment of PTEN- deficient cancers. The invention further relates to compositions comprising the miRNA for use as a PTEN agonist. L'invention concerne l'utilisation de miARN-193a pour réguler l'expression génique, en particulier l'utilisation de miARN-193a en tant qu'agoniste de PTEN. Ceci permet le traitement avantageux de cancers déficients en PTEN. L'invention concerne en outre des compositions comprenant le miARN pour une utilisation en tant qu'agoniste de PTEN.