SUBSTITUTED AMINO HETEROARYL DERIVATIVES AND COMPOSITIONS THEREOF USEFULE AS ANTIFIBROTIC COMPOUNDS

SUBSTITUTED AMINO HETEROARYL DERIVATIVES AND COMPOSITIONS THEREOF USEFULE AS ANTIFIBROTIC COMPOUNDS

The disclosure relates to heterocyclic compounds and methods for their preparation. The disclosure provides compounds that may have beneficial therapeutic activity in the treatment of a disease or condition mediated by excessive or otherwise undesirable Des1 and/or fibrotic activity. L'inventio...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: YANG, SHUXIN, FLYNN, BERNARD LUKE, LE, GIANG
Format: Patent
Sprache:eng ; fre
Schlagworte:
CHEMISTRY
HETEROCYCLIC COMPOUNDS
HUMAN NECESSITIES
HYGIENE
MEDICAL OR VETERINARY SCIENCE
METALLURGY
ORGANIC CHEMISTRY
PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES
SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:The disclosure relates to heterocyclic compounds and methods for their preparation. The disclosure provides compounds that may have beneficial therapeutic activity in the treatment of a disease or condition mediated by excessive or otherwise undesirable Des1 and/or fibrotic activity. L'invention concerne des composés hétérocycliques et leurs procédés de préparation. L'invention concerne des composés qui peuvent avoir une activité thérapeutique bénéfique dans le traitement d'une maladie ou d'un état pathologique dont la médiation est assurée par une activité Des1 et/ou fibreuse excessive ou autrement indésirable.