AZACITIDINE IN COMBINATION WITH VENETOCLAX, GILTERITINIB, MIDOSTAURIN OR OTHER COMPOUNDS FOR TREATING LEUKEMIA OR MYELODYSPLASTIC SYNDROME

Provided herein are methods for using 5-azacytidine in combination with one or more additional agents to treat diseases and disorders including acute myeloid or myelogenous leukemia (AML). Other disease and disorders those associated with abnormal cell proliferation, myelodysplastic syndromes (MDS),...

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Bibliographische Detailangaben
Hauptverfasser:	DAI, YUMIN, FRATTINI, MARK, DUNSHEE, DIANA R, ROSE, SHELONITDA, LOPES DE MENEZES, DANIEL E, BEACH, CL, JANG, JESSICA, MACBETH, KYLE
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMICAL ASPECTS OF BANDAGES, DRESSINGS, ABSORBENT PADS, ORSURGICAL ARTICLES DISINFECTION, STERILISATION, OR DEODORISATION OF AIR HUMAN NECESSITIES HYGIENE MATERIALS FOR BANDAGES, DRESSINGS, ABSORBENT PADS, OR SURGICALARTICLES MEDICAL OR VETERINARY SCIENCE METHODS OR APPARATUS FOR STERILISING MATERIALS OR OBJECTS INGENERAL PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided herein are methods for using 5-azacytidine in combination with one or more additional agents to treat diseases and disorders including acute myeloid or myelogenous leukemia (AML). Other disease and disorders those associated with abnormal cell proliferation, myelodysplastic syndromes (MDS), abnormal cell proliferation, hematologic disorders, and immune disorders, among others. La présente invention concerne des procédés d'utilisation de la 5-azacytidine en combinaison avec un ou plusieurs agents supplémentaires pour traiter des maladies et des troubles comprenant la leucémie myéloïde ou myéloblastique aiguë (LMA). D'autres maladies et troubles sont ceux associés à une prolifération cellulaire anormale, des syndromes myélodysplasiques (MDS), une prolifération cellulaire anormale, des troubles hématologiques et des troubles immunitaires, entre autres.