A METHOD AND REAGENTS FOR DIAGNOSING MEMBRANOUS NEPHROPATHY

The present invention relates to a diagnostically useful carrier coated with a recombinant polypeptide comprising SEQ ID N01, an isolated autoantibody binding specifically to a polypeptide having SEQ ID N01, a kit comprising the carrier, a method for the diagnosis of a membranous nephropathy (MN) co...

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Bibliographische Detailangaben
Hauptverfasser:	DETTMANN, INGA-MADELEINE, MINDORF, SWANTJE, PROBST, CHRISTIAN
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	BEER BIOCHEMISTRY CHEMISTRY COMPOSITIONS OR TEST PAPERS THEREFOR COMPOSITIONS THEREOF CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL ORENZYMOLOGICAL PROCESSES CULTURE MEDIA ENZYMOLOGY INVESTIGATING OR ANALYSING MATERIALS BY DETERMINING THEIRCHEMICAL OR PHYSICAL PROPERTIES MEASURING MEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEICACIDS OR MICROORGANISMS METALLURGY MICROBIOLOGY MICROORGANISMS OR ENZYMES MUTATION OR GENETIC ENGINEERING ORGANIC CHEMISTRY PEPTIDES PHYSICS PROCESSES OF PREPARING SUCH COMPOSITIONS PROPAGATING, PRESERVING OR MAINTAINING MICROORGANISMS SPIRITS TESTING VINEGAR WINE
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Beschreibung
Zusammenfassung:	The present invention relates to a diagnostically useful carrier coated with a recombinant polypeptide comprising SEQ ID N01, an isolated autoantibody binding specifically to a polypeptide having SEQ ID N01, a kit comprising the carrier, a method for the diagnosis of a membranous nephropathy (MN) comprising the step detecting the presence or absence of an autoantibody binding specifically to a polypeptide having SEQ ID NO1 in a liquid sample comprising antibodies from a subject, a use of an autoantibody binding specifically to a polypeptide having SEQ ID NO1 or a polypeptide comprising SEQ ID N01, and a aqueous solution comprising an autoantibody binding specifically to a polypeptide having SEQ ID N01.