SUBSTITUTED 1-OXO-ISOINDOLINE-5-CARBOXAMIDE COMPOUNDS, COMPOSITIONS THEREOF, AND METHODS OF TREATMENT THEREWITH

Provided herein are 1-oxo-isoindoline-5-carboxamide compounds having the following structure of Formula (I), wherein R1, R2, R3, R4 and n are as defined herein, compositions comprising an effective amount of a 1-oxo-isoindoline-5-carboxamide compound, and methods for treating or preventing disorders...

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Hauptverfasser: NAGY, MARK A, HANSEN, JOSHUA, PERRIN-NINKOVIC, SOPHIE, LEBRUN, LAURIE A, LU, CHINUN, NORTHCOTE, KATHERINE, BACULI, FRANS, PENG, SOPHIE, CORREA, MATTHEW D, LU, GANG
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Provided herein are 1-oxo-isoindoline-5-carboxamide compounds having the following structure of Formula (I), wherein R1, R2, R3, R4 and n are as defined herein, compositions comprising an effective amount of a 1-oxo-isoindoline-5-carboxamide compound, and methods for treating or preventing disorders. L'invention concerne des composés de 1-oxo-isoindoline-5-carboxamide ayant la structure suivante de formule (I), dans laquelle R1, R2, R3, R4 et n sont tels que définis dans la description, des compositions comprenant une quantité efficace d'un composé de 1-oxo-isoindoline-5-carboxamide, et des procédés de traitement ou de prévention de troubles.