BIORELEVANT COMPOSITION

A biorelevant precursor composition suitable, upon dispersing, dilution or suspension in an aqueous medium, for simulating fed-state gastric fluids of mammalian species, wherein said biorelevant precursor composition comprises a substantially solid/solid- like concentrate, a viscous gel-like concentrate, or a liquid fat dispersion/concentrate, comprising at least one primary component selected from each of the following groups of primary components comprising: i) Triglyceride and/or diglyceride and/or monoglyceride or any combinations thereof in an amount of from 1 - 70% by weight; ii) Lecithin and/or lysolecithin in an amount of from 1 - 45% by weight; iii) Carbohydrate in an amount of from 15 - 70% by weight; and iv) Water or other aqueous medium in an amount of from 1 - 70% by weight; wherein the weight ratio of total fats (one or more primary components from each of groups i) and ii) combined) : total carbohydrates (one or more primary components from group iii) combined) is between 20:1 to 1:20; and the weight ratio of glyceride : lecithin and/or lysolecithin is between 45:1 and 1:45; and in addition at least one additional component selected from at least one of the following: (i) fatty acids (between 0.01 - 15% by weight); (ii) bile acid/salt (between 0.01 - 3% by weight); (iii) enzymes (between 0.01 - 2% by weight); (iv) cholesterol, sterols (between 0.01 - 5% by weight); (v) buffer agents (between 0.01 - 4% by weight); (vi) osmotic agents (between 0.01 - 10% by weight); 52 (vii) proteins (collagen, protein hydrolysates, amino acids) (between 0.01 - 30% by weight); (viii) mucin (between 0.1 - 5% by weight); (ix) viscosity modifier (between 0.1 - 5% by weight); and (x) preservatives, stabilizers (between 0.01 - 3% by weight), such as a) anti-oxidants, b) chelating agents, c) buffers (inorganic or organic), and d) antimicrobials; all percentages being by dry weight. A method of producing these compositions is also provided. La présente invention concerne une composition de précurseur biopertinente appropriée, lors de la dispersion, de la dilution ou de la suspension dans un milieu aqueux, pour simuler des fluides gastriques à l'état alimenté d'espèces de mammifère, ladite composition de précurseur biopertinente comprenant un concentré sensiblement solide/ de type solide, un concentré de type gel visqueux ou un concentré/ dispersion de graisse liquide, comprenant au moins un composant principal choisi parmi chacun des groupes suivants de composants pr