THIENOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF
Provided are a thienoheterocyclic derivative, a preparation method therefor and the medical use thereof. In particular, provided are a thienoheterocyclic derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, the use of s...
Gespeichert in:
| Hauptverfasser: | , , , , |
|---|---|
| Format: | Patent |
| Sprache: | eng ; fre |
| Schlagworte: | |
| Online-Zugang: | Volltext bestellen |
| Tags: |
Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
|
| container_end_page | |
|---|---|
| container_issue | |
| container_start_page | |
| container_title | |
| container_volume | |
| creator | CHEN, YANG LI, XIN HE, FENG FENG, BINQIANG TAO, WEIKANG |
| description | Provided are a thienoheterocyclic derivative, a preparation method therefor and the medical use thereof. In particular, provided are a thienoheterocyclic derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, the use of same as a therapeutic agent, particularly as an ERK inhibitor, and the use of same in the preparation of a drug for treating or preventing cancers, inflammation or other proliferative diseases, wherein each substituent of general formula (I) is the same as defined in the description.
L'invention concerne un dérivé thiénohétérocyclique, son procédé de préparation et son utilisation médicale. En particulier, l'invention concerne un dérivé thiénohétérocyclique représenté par la formule générale (I), son procédé de préparation, une composition pharmaceutique contenant le dérivé, son utilisation en tant qu'agent thérapeutique, en particulier en tant qu'inhibiteur d'ERK, et son utilisation dans la préparation d'un médicament pour le traitement ou la prévention de cancers, d'une inflammation ou d'autres maladies prolifératives, chaque substituant de formule générale (I) étant tel que défini dans la description. |
| format | Patent |
| fullrecord | <record><control><sourceid>epo_EVB</sourceid><recordid>TN_cdi_epo_espacenet_CA3134405A1</recordid><sourceformat>XML</sourceformat><sourcesystem>PC</sourcesystem><sourcerecordid>CA3134405A1</sourcerecordid><originalsourceid>FETCH-epo_espacenet_CA3134405A13</originalsourceid><addsrcrecordid>eNqNikEKwjAQRbNxIeod5gAKltQDDJMJCdRMGWOhq1IkrkQL9f5Y0AO4-rz3_tpoDpGTBM6sQj01kcCxxg5z7HgPrXKLuoAkOHMO4iAHVvaigMktzkXCBq4X_gbxW7O6j4-57H67MeA5UziU6TWUeRpv5VneA6GtbF0fT1jZPy4fk_IvLA</addsrcrecordid><sourcetype>Open Access Repository</sourcetype><iscdi>true</iscdi><recordtype>patent</recordtype></control><display><type>patent</type><title>THIENOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF</title><source>esp@cenet</source><creator>CHEN, YANG ; LI, XIN ; HE, FENG ; FENG, BINQIANG ; TAO, WEIKANG</creator><creatorcontrib>CHEN, YANG ; LI, XIN ; HE, FENG ; FENG, BINQIANG ; TAO, WEIKANG</creatorcontrib><description>Provided are a thienoheterocyclic derivative, a preparation method therefor and the medical use thereof. In particular, provided are a thienoheterocyclic derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, the use of same as a therapeutic agent, particularly as an ERK inhibitor, and the use of same in the preparation of a drug for treating or preventing cancers, inflammation or other proliferative diseases, wherein each substituent of general formula (I) is the same as defined in the description.
L'invention concerne un dérivé thiénohétérocyclique, son procédé de préparation et son utilisation médicale. En particulier, l'invention concerne un dérivé thiénohétérocyclique représenté par la formule générale (I), son procédé de préparation, une composition pharmaceutique contenant le dérivé, son utilisation en tant qu'agent thérapeutique, en particulier en tant qu'inhibiteur d'ERK, et son utilisation dans la préparation d'un médicament pour le traitement ou la prévention de cancers, d'une inflammation ou d'autres maladies prolifératives, chaque substituant de formule générale (I) étant tel que défini dans la description.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2020</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201001&DB=EPODOC&CC=CA&NR=3134405A1$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,776,881,25542,76516</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20201001&DB=EPODOC&CC=CA&NR=3134405A1$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>CHEN, YANG</creatorcontrib><creatorcontrib>LI, XIN</creatorcontrib><creatorcontrib>HE, FENG</creatorcontrib><creatorcontrib>FENG, BINQIANG</creatorcontrib><creatorcontrib>TAO, WEIKANG</creatorcontrib><title>THIENOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF</title><description>Provided are a thienoheterocyclic derivative, a preparation method therefor and the medical use thereof. In particular, provided are a thienoheterocyclic derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, the use of same as a therapeutic agent, particularly as an ERK inhibitor, and the use of same in the preparation of a drug for treating or preventing cancers, inflammation or other proliferative diseases, wherein each substituent of general formula (I) is the same as defined in the description.
L'invention concerne un dérivé thiénohétérocyclique, son procédé de préparation et son utilisation médicale. En particulier, l'invention concerne un dérivé thiénohétérocyclique représenté par la formule générale (I), son procédé de préparation, une composition pharmaceutique contenant le dérivé, son utilisation en tant qu'agent thérapeutique, en particulier en tant qu'inhibiteur d'ERK, et son utilisation dans la préparation d'un médicament pour le traitement ou la prévention de cancers, d'une inflammation ou d'autres maladies prolifératives, chaque substituant de formule générale (I) étant tel que défini dans la description.</description><subject>CHEMISTRY</subject><subject>HETEROCYCLIC COMPOUNDS</subject><subject>HUMAN NECESSITIES</subject><subject>HYGIENE</subject><subject>MEDICAL OR VETERINARY SCIENCE</subject><subject>METALLURGY</subject><subject>ORGANIC CHEMISTRY</subject><subject>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</subject><subject>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><fulltext>true</fulltext><rsrctype>patent</rsrctype><creationdate>2020</creationdate><recordtype>patent</recordtype><sourceid>EVB</sourceid><recordid>eNqNikEKwjAQRbNxIeod5gAKltQDDJMJCdRMGWOhq1IkrkQL9f5Y0AO4-rz3_tpoDpGTBM6sQj01kcCxxg5z7HgPrXKLuoAkOHMO4iAHVvaigMktzkXCBq4X_gbxW7O6j4-57H67MeA5UziU6TWUeRpv5VneA6GtbF0fT1jZPy4fk_IvLA</recordid><startdate>20201001</startdate><enddate>20201001</enddate><creator>CHEN, YANG</creator><creator>LI, XIN</creator><creator>HE, FENG</creator><creator>FENG, BINQIANG</creator><creator>TAO, WEIKANG</creator><scope>EVB</scope></search><sort><creationdate>20201001</creationdate><title>THIENOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF</title><author>CHEN, YANG ; LI, XIN ; HE, FENG ; FENG, BINQIANG ; TAO, WEIKANG</author></sort><facets><frbrtype>5</frbrtype><frbrgroupid>cdi_FETCH-epo_espacenet_CA3134405A13</frbrgroupid><rsrctype>patents</rsrctype><prefilter>patents</prefilter><language>eng ; fre</language><creationdate>2020</creationdate><topic>CHEMISTRY</topic><topic>HETEROCYCLIC COMPOUNDS</topic><topic>HUMAN NECESSITIES</topic><topic>HYGIENE</topic><topic>MEDICAL OR VETERINARY SCIENCE</topic><topic>METALLURGY</topic><topic>ORGANIC CHEMISTRY</topic><topic>PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES</topic><topic>SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</topic><toplevel>online_resources</toplevel><creatorcontrib>CHEN, YANG</creatorcontrib><creatorcontrib>LI, XIN</creatorcontrib><creatorcontrib>HE, FENG</creatorcontrib><creatorcontrib>FENG, BINQIANG</creatorcontrib><creatorcontrib>TAO, WEIKANG</creatorcontrib><collection>esp@cenet</collection></facets><delivery><delcategory>Remote Search Resource</delcategory><fulltext>fulltext_linktorsrc</fulltext></delivery><addata><au>CHEN, YANG</au><au>LI, XIN</au><au>HE, FENG</au><au>FENG, BINQIANG</au><au>TAO, WEIKANG</au><format>patent</format><genre>patent</genre><ristype>GEN</ristype><title>THIENOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF</title><date>2020-10-01</date><risdate>2020</risdate><abstract>Provided are a thienoheterocyclic derivative, a preparation method therefor and the medical use thereof. In particular, provided are a thienoheterocyclic derivative represented by general formula (I), a preparation method therefor, a pharmaceutical composition containing the derivative, the use of same as a therapeutic agent, particularly as an ERK inhibitor, and the use of same in the preparation of a drug for treating or preventing cancers, inflammation or other proliferative diseases, wherein each substituent of general formula (I) is the same as defined in the description.
L'invention concerne un dérivé thiénohétérocyclique, son procédé de préparation et son utilisation médicale. En particulier, l'invention concerne un dérivé thiénohétérocyclique représenté par la formule générale (I), son procédé de préparation, une composition pharmaceutique contenant le dérivé, son utilisation en tant qu'agent thérapeutique, en particulier en tant qu'inhibiteur d'ERK, et son utilisation dans la préparation d'un médicament pour le traitement ou la prévention de cancers, d'une inflammation ou d'autres maladies prolifératives, chaque substituant de formule générale (I) étant tel que défini dans la description.</abstract><oa>free_for_read</oa></addata></record> |
| fulltext | fulltext_linktorsrc |
| identifier | |
| ispartof | |
| issn | |
| language | eng ; fre |
| recordid | cdi_epo_espacenet_CA3134405A1 |
| source | esp@cenet |
| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | THIENOHETEROCYCLIC DERIVATIVE, PREPARATION METHOD THEREFOR AND MEDICAL USE THEREOF |
| url | https://sfx.bib-bvb.de/sfx_tum?ctx_ver=Z39.88-2004&ctx_enc=info:ofi/enc:UTF-8&ctx_tim=2025-02-19T04%3A02%3A30IST&url_ver=Z39.88-2004&url_ctx_fmt=infofi/fmt:kev:mtx:ctx&rfr_id=info:sid/primo.exlibrisgroup.com:primo3-Article-epo_EVB&rft_val_fmt=info:ofi/fmt:kev:mtx:patent&rft.genre=patent&rft.au=CHEN,%20YANG&rft.date=2020-10-01&rft_id=info:doi/&rft_dat=%3Cepo_EVB%3ECA3134405A1%3C/epo_EVB%3E%3Curl%3E%3C/url%3E&disable_directlink=true&sfx.directlink=off&sfx.report_link=0&rft_id=info:oai/&rft_id=info:pmid/&rfr_iscdi=true |