TOPICAL COMPOSITIONS FOR NITRIC OXIDE RELEASE AND METHODS OF USING THE SAME

The present invention relates generally to compositions and methods of using the same. The present invention relates to a method of increasing the release of nitric oxide from an anhydrous alcohol topical gel comprising a diazeniumdiolate modified macromolecule and at least one alcohol, the method c...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: STASKO, NATHAN, DOXEY, RYAN, SABOUNI, ADAM, KOUGOULOS, ELEFTHERIOS
Format: Patent
Sprache:eng ; fre
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Beschreibung
Zusammenfassung:The present invention relates generally to compositions and methods of using the same. The present invention relates to a method of increasing the release of nitric oxide from an anhydrous alcohol topical gel comprising a diazeniumdiolate modified macromolecule and at least one alcohol, the method comprising contacting the anhydrous alcohol topical gel with a hydrogel having a pH in a range of about 4 to about 6 to provide a combined composition; and wherein the combined composition is for topical application to skin of a subject.