SYNTHESIS OF 4-CHLOROKYNURENINES AND INTERMEDIATES

The invention relates to an overall enantio-specific synthesis of 4-chlorokynurenine compounds, in particular L-4-chlorokynurenine, with improved yields. Large-scale syntheses are disclosed. The invention also relates to novel intermediates in the synthesis of L-4-chlorokynurenine. L'invention...

Ausführliche Beschreibung

Gespeichert in:
Bibliographische Detailangaben
Hauptverfasser: EISENREICH, EMERICH, LEEMING, PETER, LEVIN, DANIEL, LIU, XUEJUN KARL
Format: Patent
Sprache:eng ; fre
Schlagworte:
Online-Zugang:Volltext bestellen
Tags: Tag hinzufügen
Keine Tags, Fügen Sie den ersten Tag hinzu!
Beschreibung
Zusammenfassung:The invention relates to an overall enantio-specific synthesis of 4-chlorokynurenine compounds, in particular L-4-chlorokynurenine, with improved yields. Large-scale syntheses are disclosed. The invention also relates to novel intermediates in the synthesis of L-4-chlorokynurenine. L'invention concerne une synthèse globale énantio-spécifique de composés de 4-chlorokynurénine, en particulier de L-4-chlorokynurénine, avec des rendements améliorés. L'invention concerne également des synthèses à grande échelle. L'invention concerne également de nouveaux intermédiaires dans la synthèse de L-4-chlorokynurénine.