METHODS OF PRODUCING HIGH DIVERSITY PEPTIDE LIBRARIES AND PROMOTING PROTEIN FOLDING

The disclosure provides a peptide library with increased peptide diversity. The increase in peptide diversity can occur via cleavage of particular amino acids within a peptide. The disclosure further provides a method for promoting folding of a peptide into an active conformation. L'invention c...

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Hauptverfasser: AFZELIUS, ELLEN LOVISA LARSDOTTER, YOSEFSON, OHAD, ROSCOE, BENJAMIN PETER, MABRY, GEORGE ROBERT III, ROGOV, PETER LYUBOMIROV, VAIDYA, HARSH JAYESHKUMAR, SWAIN, JOANNA FELTHAM
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creator AFZELIUS, ELLEN LOVISA LARSDOTTER
YOSEFSON, OHAD
ROSCOE, BENJAMIN PETER
MABRY, GEORGE ROBERT III
ROGOV, PETER LYUBOMIROV
VAIDYA, HARSH JAYESHKUMAR
SWAIN, JOANNA FELTHAM
description The disclosure provides a peptide library with increased peptide diversity. The increase in peptide diversity can occur via cleavage of particular amino acids within a peptide. The disclosure further provides a method for promoting folding of a peptide into an active conformation. L'invention concerne une banque peptidique ayant une diversité de peptides accrue. L'augmentation de la diversité de peptides peut se produire par clivage d'acides aminés particuliers dans un peptide. L'invention concerne en outre un procédé permettant de favoriser le pliage d'un peptide dans une conformation active.
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subjects CHEMISTRY
COMBINATORIAL CHEMISTRY
LIBRARIES, e.g. CHEMICAL LIBRARIES, IN SILICOLIBRARIES
METALLURGY
ORGANIC CHEMISTRY
PEPTIDES
title METHODS OF PRODUCING HIGH DIVERSITY PEPTIDE LIBRARIES AND PROMOTING PROTEIN FOLDING
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