CYCLIN-DEPENDENT KINASE INHIBITORS

Described herein are compounds and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, methods of treatment, and medical uses. The compounds described herein are modulators of cyclin-dependent kinases, and are useful in the treatment or alleviation of protein kinase associa...

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Bibliographische Detailangaben
Hauptverfasser: KATAMREDDY, SUBBA R, SAVED, YOUSRY, RAMIREDDY, NARESH
Format: Patent
Sprache:eng ; fre
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Zusammenfassung:Described herein are compounds and their pharmaceutically acceptable salts, pharmaceutical compositions thereof, methods of treatment, and medical uses. The compounds described herein are modulators of cyclin-dependent kinases, and are useful in the treatment or alleviation of protein kinase associated disorders, including cancer, infectious diseases, autoimmune diseases, or cardiovascular diseases. L'invention concerne des composés et leurs sels pharmaceutiquement acceptables, des compositions pharmaceutiques de ceux-ci, des procédés de traitement et des utilisations médicales. Les composés de l'invention sont des modulateurs de kinase cycline-dépendants, et sont utiles dans le traitement ou le soulagement de troubles associés à la protéine kinase, notamment le cancer, les maladies infectieuses, les maladies auto-immunes, ou les maladies cardiovasculaires.