SUBSTITUTED ISOINDOLINONES

Substituted isoindolinones of Formula (I), methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat or ameliorate diseases, disorders, or conditions associated with protein malfunction, such as cancer, are p...

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Bibliographische Detailangaben
Hauptverfasser:	CHOURASIA, APARAJITA HOSKOTE, LAM, IMELDA, TORRES, EDUARDO, MERCURIO, FRANK, SULLIVAN, ROBERT, CHAN, KYLE W. H, FUNG, LEAH, ERDMAN, PAUL E
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Substituted isoindolinones of Formula (I), methods of making such compounds, pharmaceutical compositions and medicaments comprising such compounds, and methods of using such compounds to treat or ameliorate diseases, disorders, or conditions associated with protein malfunction, such as cancer, are provided. L'invention concerne des isoindolinones substituées de formule (I), des procédés de fabrication de tels composés, des compositions pharmaceutiques et des médicaments comprenant de tels composés, et des procédés d'utilisation de tels composés pour traiter ou améliorer des maladies, des troubles ou des états associés à un dysfonctionnement des protéines, tels que le cancer.