BORON CONTAINING PDE4 INHIBITORS

The present invention relates to boron containing compounds of Formula (l): X-Y-Z, for example, compounds of the formula (la): that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating diseases, conditions,...

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Bibliographische Detailangaben
Hauptverfasser:	JONES, PETER, YEOH, THEAN YEOW, PLATTNER, JACOB JOHN, AKAMA, TSUTOMU, JACOBS, ROBERT TOMS, PERRY, MATTHEW ALEXANDER, TORELLA, RUBBEN FEDERICO, ZHOU, YASHEEN, STROHBACH, JOSEPH WALTER, ODERINDE, MARTINS SUNDAY, BLAKEMORE, DAVID CLIVE, LIMBURG, DAVID CHRISTOPHER
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAININGELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN,SULFUR, SELENIUM OR TELLURIUM CHEMISTRY HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	The present invention relates to boron containing compounds of Formula (l): X-Y-Z, for example, compounds of the formula (la): that inhibit phosphodiesterase 4 (PDE4). The invention also encompasses pharmaceutical compositions containing these compounds and methods for treating diseases, conditions, or disorders ameliorated by inhibition of PDE4. Il est décrit des composés contenant du bore de formule (I) : X-Y-Z, par exemple, des composés de la formule (la) : 5 inhibant la phosphodiestérase 4. Il est également décrit des compositions pharmaceutiques contenant ces composés et des méthodes de traitement de maladies, d'états ou de troubles améliorés par l'inhibition de phosphodiestérase 4.