AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY
Provided are a JAK kinase inhibitor, preparation therefor and the use thereof. In particular, provided is a compound as shown by formula (I), wherein the definition of each group is as described in the description. The compound has an excellent JAK inhibitory activity, and therefore can be used for...
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| creator | LIU, SHENGYANG XIE, XIAOPING ZHENG, MINGWEI DENG, JIANWEN SHANG, KE JIANG, LEI ZHANG, JIANHUA SHOU, JIANYONG FENG, ZHIYONG ZHAO, HAIXIA XU, YUAN WU, DANYI MAO, XUDONG |
| description | Provided are a JAK kinase inhibitor, preparation therefor and the use thereof. In particular, provided is a compound as shown by formula (I), wherein the definition of each group is as described in the description. The compound has an excellent JAK inhibitory activity, and therefore can be used for preparing pharmaceutical compositions for treating cancers and other diseases associated with JAK activity.
L'invention concerne un inhibiteur de JAK kinase, sa préparation et son utilisation. En particulier, l'invention concerne un composé tel que représenté par la formule (I), la définition de chaque groupe étant telle que décrite dans la description. Le composé a une excellente activité inhibitrice de JAK, et peut donc être utilisé pour préparer des compositions pharmaceutiques pour traiter des cancers et d'autres maladies associées à une activité de JAK. |
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L'invention concerne un inhibiteur de JAK kinase, sa préparation et son utilisation. En particulier, l'invention concerne un composé tel que représenté par la formule (I), la définition de chaque groupe étant telle que décrite dans la description. Le composé a une excellente activité inhibitrice de JAK, et peut donc être utilisé pour préparer des compositions pharmaceutiques pour traiter des cancers et d'autres maladies associées à une activité de JAK.</description><language>eng ; fre</language><subject>CHEMISTRY ; HETEROCYCLIC COMPOUNDS ; HUMAN NECESSITIES ; HYGIENE ; MEDICAL OR VETERINARY SCIENCE ; METALLURGY ; ORGANIC CHEMISTRY ; PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES ; SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS</subject><creationdate>2023</creationdate><oa>free_for_read</oa><woscitedreferencessubscribed>false</woscitedreferencessubscribed></display><links><openurl>$$Topenurl_article</openurl><openurlfulltext>$$Topenurlfull_article</openurlfulltext><thumbnail>$$Tsyndetics_thumb_exl</thumbnail><linktohtml>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230711&DB=EPODOC&CC=CA&NR=3113732C$$EHTML$$P50$$Gepo$$Hfree_for_read</linktohtml><link.rule.ids>230,308,780,885,25563,76318</link.rule.ids><linktorsrc>$$Uhttps://worldwide.espacenet.com/publicationDetails/biblio?FT=D&date=20230711&DB=EPODOC&CC=CA&NR=3113732C$$EView_record_in_European_Patent_Office$$FView_record_in_$$GEuropean_Patent_Office$$Hfree_for_read</linktorsrc></links><search><creatorcontrib>LIU, SHENGYANG</creatorcontrib><creatorcontrib>XIE, XIAOPING</creatorcontrib><creatorcontrib>ZHENG, MINGWEI</creatorcontrib><creatorcontrib>DENG, JIANWEN</creatorcontrib><creatorcontrib>SHANG, KE</creatorcontrib><creatorcontrib>JIANG, LEI</creatorcontrib><creatorcontrib>ZHANG, JIANHUA</creatorcontrib><creatorcontrib>SHOU, JIANYONG</creatorcontrib><creatorcontrib>FENG, ZHIYONG</creatorcontrib><creatorcontrib>ZHAO, HAIXIA</creatorcontrib><creatorcontrib>XU, YUAN</creatorcontrib><creatorcontrib>WU, DANYI</creatorcontrib><creatorcontrib>MAO, XUDONG</creatorcontrib><title>AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY</title><description>Provided are a JAK kinase inhibitor, preparation therefor and the use thereof. In particular, provided is a compound as shown by formula (I), wherein the definition of each group is as described in the description. The compound has an excellent JAK inhibitory activity, and therefore can be used for preparing pharmaceutical compositions for treating cancers and other diseases associated with JAK activity.
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L'invention concerne un inhibiteur de JAK kinase, sa préparation et son utilisation. En particulier, l'invention concerne un composé tel que représenté par la formule (I), la définition de chaque groupe étant telle que décrite dans la description. Le composé a une excellente activité inhibitrice de JAK, et peut donc être utilisé pour préparer des compositions pharmaceutiques pour traiter des cancers et d'autres maladies associées à une activité de JAK.</abstract><oa>free_for_read</oa></addata></record> |
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| subjects | CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS |
| title | AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY |
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