AROMATIC HETEROCYCLIC COMPOUND WITH KINASE INHIBITORY ACTIVITY

Provided are a JAK kinase inhibitor, preparation therefor and the use thereof. In particular, provided is a compound as shown by formula (I), wherein the definition of each group is as described in the description. The compound has an excellent JAK inhibitory activity, and therefore can be used for...

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Bibliographische Detailangaben
Hauptverfasser:	LIU, SHENGYANG, XIE, XIAOPING, ZHENG, MINGWEI, DENG, JIANWEN, SHANG, KE, JIANG, LEI, ZHANG, JIANHUA, SHOU, JIANYONG, FENG, ZHIYONG, ZHAO, HAIXIA, XU, YUAN, WU, DANYI, MAO, XUDONG
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	CHEMISTRY HETEROCYCLIC COMPOUNDS HUMAN NECESSITIES HYGIENE MEDICAL OR VETERINARY SCIENCE METALLURGY ORGANIC CHEMISTRY PREPARATIONS FOR MEDICAL, DENTAL, OR TOILET PURPOSES SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS ORMEDICINAL PREPARATIONS
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Beschreibung
Zusammenfassung:	Provided are a JAK kinase inhibitor, preparation therefor and the use thereof. In particular, provided is a compound as shown by formula (I), wherein the definition of each group is as described in the description. The compound has an excellent JAK inhibitory activity, and therefore can be used for preparing pharmaceutical compositions for treating cancers and other diseases associated with JAK activity. L'invention concerne un inhibiteur de JAK kinase, sa préparation et son utilisation. En particulier, l'invention concerne un composé tel que représenté par la formule (I), la définition de chaque groupe étant telle que décrite dans la description. Le composé a une excellente activité inhibitrice de JAK, et peut donc être utilisé pour préparer des compositions pharmaceutiques pour traiter des cancers et d'autres maladies associées à une activité de JAK.