TRAMADOL HBR-CELECOXIB CO-CRYSTAL

The present invention provides a novel 1:1 co-crystal of (rac)-tramadol hydrobromide-celecoxib and processes for the preparation of the same by reacting (rac)-tramadol with hydrobromic acid and celecoxib. It also provides crystalline form of (rac)-tramadol hydrobromide. La présente invention concern...

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Bibliographische Detailangaben
Hauptverfasser:	JETTI, RAMAKOTESWARA RAO, JAYACHANDRA, SURESHBABU, GOLIVI, RAMAMOHANA RAO
Format:	Patent
Sprache:	eng ; fre
Schlagworte:	ACYCLIC OR CARBOCYCLIC COMPOUNDS CHEMISTRY HETEROCYCLIC COMPOUNDS METALLURGY ORGANIC CHEMISTRY
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Beschreibung
Zusammenfassung:	The present invention provides a novel 1:1 co-crystal of (rac)-tramadol hydrobromide-celecoxib and processes for the preparation of the same by reacting (rac)-tramadol with hydrobromic acid and celecoxib. It also provides crystalline form of (rac)-tramadol hydrobromide. La présente invention concerne un nouveau co-cristal 1 : 1 de bromhydrate de (rac)-tramadol-célécoxib et des procédés de préparation de celui-ci par réaction de (rac)-tramadol avec de l'acide bromhydrique et du célécoxib. L'invention concerne également une forme cristalline de bromhydrate de (rac)-tramadol.